Quantitative Diffractometric Biosensing

9. March 2021

Blickenstorfer, Y. et al. Phys. Rev. Applied 15, 034023 (2021)


This paper provides formulas for the quantification of the amount of analyte that has bound to any two dimensional diffractometric biosensor. Prior to this publication the majority of published diffractometric biosensors were not quantitative. This severely impeded assay independent comparison to established refractometric biosensors such as surface plasmon resonance. With this publication one can now compare the sensitivity and resolution of any diffractometric biosensor to established refractometric devices (Frutiger et al. 2020). Read more about it in our latest paper.