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Phage display is a selection technique used in biopharmaceutical manufacturing to isolate proteins with desired properties (e.g. specificity, affinity, stability) for a given effect. The advantage of this technique is that it enables a direct link between an expressed protein and its genetic sequence (genotype-phenotype linkage), as a protein’s genetic sequence can directly be extracted from an isolated phage. The process of phage display is shown below.
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