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Focal Molography in a Pandemic

The COVID-19 pandemic has led to transformative biopharmaceutical technologies. Could focal molography play a role in that field? After over a year and a half, the COVID-19 pandemic is still ongoing and is showing no signs of slowing down. It has proven that despite the development of our world on all fronts, we were ill-equipped to handle a pandemic.

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AIDS red ribbon

The Molecular Detective

SARS-Cov-2 is not the only virus responsible for a pandemic this century; the human immunodeficiency virus, more commonly known as HIV, is another. Unlike SARS-Cov-2 however, HIV infection cannot be cured; transmission is irreversible.

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schematic of focal molography

Focal Molography – A New Frontier in Biosensing

Focal molography was introduced in the latest blog article as a novel technology capable of detecting molecular interactions, without acquiring any environmental noise. What other advantages does this technology provide?

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An Introduction to Focal Molography

Although SPR offers many advantages in biosensing, its potential is hampered by one key factor: environmental noise. Has any biosensor ever overcome this challenge? A novel technology, known as focal molography, is emerging as a contender in noise-free biosensing.

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The Big Con of SPR – And How to Solve it

Understanding the environmental noise problem encountered and the high measurement precision needed in with surface plasmon resonance (and all refractometric biosensors) requires fundamental knowledge not only of how the desired binding signal is acquired in this technique, but also why we detect changes (noise) we are not interested in measuring.

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SPR explanation diagram

Surface Plasmon Resonance (SPR)

One of the most common label-free assays for detecting molecular interactions is surface plasmon resonance (SPR). In this article, we discuss what it s used for, how it works, and some of its key advantages and disadvantages.

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