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Application note

Fast and convenient hit validaton for DNA-encoded libraries

DEL ·Nov, 2024
Fast and convenient hit validaton for DNA-encoded libraries

The document describes the integration of focal Molography with DNA-encoded library (DEL) technology to streamline the screening and validation of small molecule hits in drug discovery. This method allows simultaneous kinetic characterization of up to 54 compounds in a single step, enhancing efficiency and enabling detailed insights into binding dynamics in physiologically relevant environments.

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More resources

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