lino Biotech

Discover Molecular Interactions

About Us

lino Biotech is the world´s only provider of Focal Molography – an entirely new method for measuring molecular interactions in living cells or crude biological samples. The broadly patented technology offers label-free detection assays while eliminating signal disturbances due to temperature changes or non-specific binding. lino Biotech was incorporated in Zürich, Switzerland, in March 2020 with the aim to make cell therapies more cost effective and accessible for a broader patient population by offering new quality control method that every cell therapy manufacturer can use to improve their production and development process.

Label-Free

Focal Molography is a label-free interaction technology able to characterize a plurality of important interactions.

Stable

Due to its nano-sized, self-referencing principle Focal Molography offers a unique signal stability regarding environmental influences.

Automated

Due to its fast read-outs and simple use, focal molography can be easily automated, which enables increased throughput and minimal hands-on time.

Multiplexed

Due to its label-free nature, focal molography is well suited for multiplexed assays, minimizing cross-talk between reagents.

Fast

No pre-equilibration with buffer or temperature stabilizations of the sensor is required for the measurement. This allows for an immediate start of the measurement.

Complex-Samples

By its physical nature, focal molography is compatible with complex media and cell-based assays allowing a new data dimension for scientists.

Current Approach

Trying to tackle analytical challenges, device manufacturers have ramped up engineering and data processing efforts. For customers, these strategies result in unfavorable solutions:

  • Extensive sample preparation
  • Risk of artifacts due to sample group
  • Complex assay design
  • Expensive equipment and sensor

Our
Solution

lino´s biosensors and readers enable much faster and more accurate characterization of cell therapy products while at the same time helping the manufactures to substantially reduce production cost. Speeding up product QC, lowering production cost and improving safety of cell and gene therapies.

  • No sample purification
  • Simple assay design
  • Faster results
  • Offering novel QC options
Bioprocess
Fast at-line determination of product quality and biological relevant status information on process parameters
Drug Screening
Real-time and label-free characterization of drug candidates in living cells.
Diagnostics
Simple and robust quantification of biomarkers for health applications.

Focal Molography

In short, focal molography is a nanotechnology-based method that cleverly combines photolithography, molecular self-assembly and state-of-the-art optical technology. It is a truly interdisciplinary technology, inspired by physics, tailored for biology and implemented for biomolecular interaction analysis.

IP Rights Cover Most Relevant Markets

We have a strong global IP protection with our broad and partly granted patent families.

lino has an exclusive world-wide license for 13 patents and patent applications.

Registered trademarks lino®, Molography®, Moloreader®

Latest news on Focal Molography

We’ve been researching focal molography for over 7 years and have an extensive track record of published papers in the field.

Focal Molography, A Guide Inside Cellular Pathways

The COVID-19 pandemic has led to transformative biopharmaceutical technologies. Could focal molography play a role in that field? After over a year and a half, the COVID-19 pandemic is still ongoing and is showing no signs of slowing down. It has proven that despite the development of our world on all fronts, we were ill-equipped to handle a pandemic.

Read More »

Focal Molography Beyond Healthcare- Feeding the Future

The COVID-19 pandemic has led to transformative biopharmaceutical technologies. Could focal molography play a role in that field? After over a year and a half, the COVID-19 pandemic is still ongoing and is showing no signs of slowing down. It has proven that despite the development of our world on all fronts, we were ill-equipped to handle a pandemic.

Read More »

Current Challenges in CGT Manufacturing

The COVID-19 pandemic has led to transformative biopharmaceutical technologies. Could focal molography play a role in that field? After over a year and a half, the COVID-19 pandemic is still ongoing and is showing no signs of slowing down. It has proven that despite the development of our world on all fronts, we were ill-equipped to handle a pandemic.

Read More »

Founder Team

Dr. Mirko Stange

Dr. Volker Gatterdam

Dr. Andreas Frutiger

Dr. Tilman Hoss

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