Videos and Webinars

Discovery on Target 2026: From Living-Cell GPCRs to On-DNA DEL Hits

Dr. Volker Gatterdam

Market Development Manager·lino Biotech AG

Label-free kinetics on GPCRs in living cells and on-DNA validation of DEL hits, measured in crude matrices without purification. Recorded at Discovery on Target 2026 in Boston.

Development of an Fc-Capturing Protein for High-Throughput Screening at Miltenyi Biotec

Artem Siemens

Team Coordinator, Binder Discovery Group·Miltenyi Biotec

Recorded at the 3rd focal Molography User Meeting, Artem Siemens (Miltenyi Biotec) shows how a homodimeric capture nanobody, immobilized by DNA-directed immobilization (DDI), ...

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Focal molography for the Fc receptor profiling of therapeutic anti-IgE antibodies

Dr. Paul Engeroff

University of Bern

A multiplex Fc receptor panel on focal molography maps where omalizumab, ligalizumab and their immune complexes with IgE and allergen bind, across all human Fc gamma and IgE ...

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Focal Molography Enables Rapid Evaluation of Miniprotein Plasma Protein Binding

Alyssa Anderson

Head of Protein Characterization·AI Proteins

Plasma protein binding of 15 designed miniproteins measured directly in plasma on one 64-plex chip, validated against ultracentrifugation and extended by kinetic information.

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Measuring the affinity of DNA-small molecule conjugates to target proteins, application to PROTACs

Prof. Andreas Brunschweiger

University of Würzburg

Focal molography measures how ligand, linker and oligonucleotide shape the target binding of DNA-small molecule conjugates, from DNA-conjugated PROTACs on the E3 ligase VHL to hit ...

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lino Update: New Reagents, Software Features and Developments

Sophia Zhai, Alexander Geiger, Lukas Heuberger

lino Biotech AG

New oligo adapters for DEL hit validation and for binders straight from lysate, four multiplex panels for antibody developability, and guided software workflows for the MACS ...

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Molography for integrin-mediated cancer cell adhesion

Szabolcs Novák

HUN-REN Centre for Energy Research

Focal molography follows how living HeLa cancer cells adhere to RGD-functionalized sensor chips and separates where integrins bind from how much mass arrives, revealing three ...

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Label-Free CAR-T Profiling by Focal Molography: Quantification, Antigen Engagement and Receptor Fate

Prof. Dominik Meinel

FHNW

Focal molography profiles CAR-T cells label-free on living cells: it quantifies CAR receptors, shows antigen engagement within one hour and follows what happens to the receptor ...

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On-DNA Kinetics at Philochem: What SPR Cannot Deliver

Nicholas Favalli

Group Leader, Chemistry R&D·Philochem AG, Zurich

Kinetic profiles for DEL hits that Biacore SPR and fluorescence polarization could not resolve, obtained directly on-DNA with focal molography.

DEL Hit Validation: The On-DNA Advantage

Joshua Alper, PhD

Principal Consultant·Alper Consulting, LLC

Why on-DNA binding confirmation matters at the pharma-portfolio level, and how focal molography enables validation in biologically relevant matrices.

Focal Molography in Complex Media

Prof. Dominik Meinel

Professor of Biophysics·FHNW Muttenz

In this live webinar, Prof. Dominik Meinel (FHNW) presents how focal molography enables label-free biomolecular interaction analysis in complex media. The examples include serum, ...

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Novalix 2025: Biophysics in Drug Discovery

Dr. Andreas Frutiger

Head of R&D·lino Biotech AG

Fast and label-free kinetic characterization of up to 54 DEL hits in one go, on-DNA and without off-DNA synthesis.

How scientists use MACS Matchmaker

Multiple researchers

Researchers explain how focal molography delivers sensitivity, robustness and kinetic precision in real biological samples.