One on-DNA ligand against many targets: selectivity profiling for DEL hit validation
On-DNA oncoFAP profiled against human, mouse and canine FAP and five unrelated proteins on one focal molography chip layout. Full kinetics on every species variant, flat responses on every control, and a clear construct-design rule: a double-stranded DNA tag abolishes binding.
More videos and webinars
14:19
Sep 9, 2026
Development of an Fc-Capturing Protein for High-Throughput Screening at Miltenyi Biotec
Artem Siemens
Capture and immobilization · Antibodies and Fc biology
Recorded at the 3rd focal Molography User Meeting, Artem Siemens (Miltenyi Biotec) shows how a homodimeric capture nanobody, immobilized by DNA-directed immobilization (DDI), ...
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31:56
Sep 9, 2026
Focal molography for the Fc receptor profiling of therapeutic anti-IgE antibodies
Dr. Paul Engeroff
Antibodies and Fc biology
A multiplex Fc receptor panel on focal molography maps where omalizumab, ligalizumab and their immune complexes with IgE and allergen bind, across all human Fc gamma and IgE ...
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26:18
Sep 9, 2026
Focal Molography Enables Rapid Evaluation of Miniprotein Plasma Protein Binding
Alyssa Anderson
Complex media
Plasma protein binding of 15 designed miniproteins measured directly in plasma on one 64-plex chip, validated against ultracentrifugation and extended by kinetic information.
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