Plug and Play sensor functionalization with DNA adaptors
Only one injection away from your custom functionalization
Our DNA adaptors provide a powerful and flexible way to functionalize Lino Biotech’s oligo sensor chips. Adaptors can be conjugated to any of the 64 proprietary DNA sequences complementary to the chip surface. With a simple injection, the adaptor hybridizes to its matching oligo, instantly preparing the sensor with your desired functionality. Your (tagged) ligand can then be directly injected for binding studies.
When the experiment is complete, simply apply our standard regeneration solution – no further optimization required – and the chip is immediately ready for the next interaction study.
Unique Features:
Full sensor design flexibility – easily tailor the sensor surface to your assay needs
No optimization of regeneration protocols – seamless experimental turnaround
Multiplexing capabilities – consecutive injection of adaptors with different oligos enables parallel or comparative studies
With this adaptable approach, researchers gain unmatched versatility in designing and executing biomolecular interaction assays.
Anti-Fc Adaptor:
Tailored for Fc regions of antibodies. Based on Protein-A/G, recognizes most Human-IgG molecules.
Ideal for nonmodified proteins. Works the same way as the well-known EDC/NHS chemistry, but with more control and an easy way to regenerate the immobilized molecules.
Strep-Tactin Adaptor:
Directed against the highly affine Strep-Tactin Tag. Preferentially use this tag in your expression system for affine binders over the His-tag, which is not suitable for analyzing strong interactions.
