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Same target, different stickiness: polyreactivity of therapeutic antibodies

lino Biotech AG ·Oct 2026
Same target, different stickiness: polyreactivity of therapeutic antibodies
Multiplexing

Six clinical antibodies, including two same-target pairs, ranked by polyreactivity against an eight-ligand panel on one focal molography chip. Briakinumab scored 69-fold above ustekinumab, ravulizumab at least tenfold above eculizumab, each with its ligand fingerprint.